FISHER SCIENTIFIC -- TRICHLOROTRIFLUOROETHANE  -- -
<pre>=====================  Product Identification  =====================

Product ID:TRICHLOROTRIFLUOROETHANE
MSDS Date:11/21/1994
FSC:NIIN:Submitter:N EN
Status Code:A
=== Responsible Party ===
Company Name:FISHER SCIENTIFIC
Address:1 REAGENT LANE
City:FAIRLAWN
State:NJ
ZIP:07410
Country:US
Info Phone Num:201-796-7100
Emergency Phone Num:800-424-9300
Chemtrec Ind/Phone:(800)424-9300
CAGE:1B464
=== Contractor Identification ===
Company Name:FISHER SCIENTIFIC CO.  CHEMICAL MFG DIV
Address:1 REAGENT LANE
Box:City:FAIRLAWN
State:NJ
ZIP:07410-2802
Country:US
Phone:201-796-7100
CAGE:1B464
Company Name:SCIENTIFIC SUPPLY AND EQUIPMENT INC
Address:926 POPLAR PL
Box:22607
City:SEATTLE
State:WA
ZIP:98144
Country:US
Phone:206-324-8550
CAGE:6M140

=============  Composition/Information on Ingredients  =============

Ingred Name:1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE
CAS:76-13-1
RTECS #:KJ4000000
= Wt:100.
OSHA PEL:7600 MG/M3;1000 PPM
ACGIH TLV:7670 MG/M3;1000 PPM
ACGIH STEL:9590 MG/M3;1250 PPM
Ozone Depleting Chemical:1

=====================  Hazards Identification  =====================

LD50 LC50 Mixture:LD50: (ORAL,RAT) 43 GM/KG
Routes of Entry: Inhalation:YES  Skin:YES  Ingestion:YES
Reports of Carcinogenicity:NTP:NO    IARC:NO	OSHA:NO
Health Hazards Acute and Chronic:1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE
    (FREON TF): NARCOTICS/SIMPLE ASPHYXIANT. 4500 PPM IMMED DANGEROUS
    TO LIFE/HLTH. ACUTE: MAY CAUSE MILD IRRIT OF MUC MEMB OF UPPER RESP
    TRACT. MAY BE ANESTH & CAUSE  CNS DEPRESS W/DROW & ARRHYS. HUMANS
    EXPOSED TO 2500-4500 PPM FOR 30-100 MINS SHOWED SIGNIFICANT
    IMPAIRMENT OF MANUAL DEXTERITY & VIGILANCE, LOSS OF CONC,
    SOMNOLENCE & HEAVINESS IN HEAD, WHICH DISAPPE ARED 15 MINS AFTER
    EXPOS ENDED. SIMPLE ASPHYX MAY OCCUR @ HIGH CONCS. OVEREXP COULD
    RSLT IN EPINEPHINE SENSITIZ OF HEART & SUBSEQUENTLY MAY CAUSE DEATH
    FROM VENTRICULAR FIBRILLATION UNDER (EFTS OF OVE REXP)
Effects of Overexposure:HLTH HAZS: PHYSICAL/EMOTIONAL STRESS. DOGS
    EXPOSED TO 11,000-13,000 PPM FOR 6 HRS EXPERIENCED VOMIT, LETHARGY,
    NERVOUSNESS, & TREMORS. ALL SYMPS WERE REVERSIBLE W/IN 15 MINS. IN
    EXPERIMENTAL ANIMALS,  VARIABLE DEGREES OF CARDIODYNAMIC EFTS THAT
    INCL TACHYCARDIA, MYOCARDIAL DEPRESS, & HYPOTENSION HAVE BEEN
    REPORTED. PULM EDEMA & SEV VENTRICULAR DYSRHYTHMIA MAY RSLT FROM
    INHAL OF FREONS. CHLOROFLUORO CARBON (CFC) MATLS HAVE PRDCED
    SENSITIZ OF MYOCARDIUM TO EPINEPHRINE IN LAB ANIMALS & COULD HAVE
    SIMILAR EFT IN HUMANS. ADRENOMIMETICS (I.E., EPINEPHRINE) (SUPDAT)
Medical Cond Aggravated by Exposure:PERSONS WITH PRE-EXISTING SKIN
    DISORDERS, IMPAIRED CARDIOVASCULAR FUNCTION, PARTICULARLY CARDIAC
    ARRYTHMIAS OR IMPAIRED RESPIRATORY FUNCTION.

=======================  First Aid Measures  =======================

First Aid:INHAL: REMOVE TO FRESH AIR IMMED. PERFORM ARTF RESP IF NEC.
    KEEP PERSON WARM & AT REST. TREAT SYMPTOMATICALLY & SUPPORTIVELY.
    GET MED ATTN IMMED. SKIN: REMOVE CONTAMD CLTHG & SHOES IMMED. WASH
    W/SOAP  OR MILD DETERGENT & LG AMTS OF WATER UNTIL NO EVID OF CHEM
    REMAINS (@ LST 15-20 MINS). GET MED ATTN IMMED. EYES: WASH IMMED
    W/LG AMTS OF WATER/NORMAL SALINE, OCCASNLY LIFTING UPPER & LOWER
    LIDS, UNTIL  NO EVID OF CHEM REMAINS (@ LST 15 MINS). GET MED ATTN
    IMMED. INGEST: IF VOMIT OCCURS, KEEP HEAD LOWER THAN HIPS TO HELP
    PVNT ASPIR. TREAT SYMPTOMATICALLY (TRANSPORT INFO)

=====================  Fire Fighting Measures  =====================

Autoignition Temp:=680.C, 1256.F
Extinguishing Media:DRY CHEM, CO&2, WATER SPRAY/REGULAR FOAM. FOR LGR
    FIRES, USE WATER SPRAY, FOG/ REGULAR FOAM. (1993 EMERG RESPONSE
    GUIDEBOOK, RSPA P 5800.6). USE AGENTS SUITABLE FOR (TRANSPORT INFO)
Fire Fighting Procedures:WEAR NIOSH APPRVD PRESSURE DEMAND SCBA & FULL
    PROTECTIVE EQUIPMENT . MOVE CONTAINER FROM FIRE AREA IF YOU CAN DO
    IT W/OUT RISK. DO NOT SCATTER SPILLED MATL W/HIGH-PRESSURE WATER
    STREAMS. DIKE FI RE-CONTROL WATER FOR LATER DISP (1993 EMER
    RESPONSE GUIDEBOOK, RSPA P 5800.6, GUIDE PG 31).
Unusual Fire/Explosion Hazard:NEGLIGIBLE FIRE HAZARD WHEN EXPOSED TO
    HEAT OR FLAMES. THERMAL DECOMPOSITION PRODUCTS MAY INCLUDE
    CHLORIDES, FLUORIDES & PHOSGENE .

==================  Accidental Release Measures  ==================

Spill Release Procedures:OCCUPATIONAL SPILL: STOP LEAK IF YOU CAN DO IT
    W/OUT RISK. FOR SMALL SPILLS, TAKE UP W/SAND OR OTHER ABSORBENT
    MATERIAL AND PLACE INTO CLEAN, DRY CONTAINERS FOR LATER DISPOSAL.
    KEEP UNNECESSARY PEOPLE  AWAY. ISOLATE HAZARD AREA AND DENY ENTRY.

======================	Handling and Storage  ======================

Handling and Storage Precautions:STORE AWAY FROM INCOMPATIBLE
    SUBSTANCES. KEEP IN A TIGHTLY CLOSED CONTAINER. STORE IN A COOL,
    DRY, VENTILATED AREA. OBSERVE ALL FEDERAL, STATE AND LOCAL
    REGULATIONS WHEN STORING THIS SUBSTANCE.
Other Precautions:NO SMOKING IN AREA OF USE. DO NOT USE IN GENERAL
    VICINITY OF ARC WELDING, OPEN FLAMES OR HOT SURFACES. HEAT AND/OR
    UV RADIATION MAY CAUSE FORMATION OF CHLORIDES, FLUORIDES AND
    PHOSGENE .

=============  Exposure Controls/Personal Protection  =============

Respiratory Protection:FOLLOWING RESPS & MAX USE CONCS ARE REC BY U.S.
    DEPT OF HLTH & HUMAN SERVICES, NIOSH POCKET GUIDE TO CHEM HAZS;
    NIOSH CRITERIA DOCUMENTS/BY U.S. DEPT OF LABOR, 29 CFR 1910 SUBPART
    2. SPECIFIC RESP SEL ECTED MUST BE BASED ON CONTAM LEVS FOUND IN
    WORKPLACE, MUST NOT EXCEED WORKING LIMS OF RESP & BE APPRVD BY
    NIOSH. 4500 PPM - ANY NIOSH APPRVD(TRANSPORT INFO)
Ventilation:PROVIDE GENERAL DILUTION VENTILATION TO MEET PUBLISHED
    EXPOSURE LIMITS.
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH & DELUGE SHOWER MEETING ANSI DESIGN
    CRITERIA . EMPLOYEE MUST WEAR APPROP PROT (IMPERVIOUS) CLTHG &
    EQUIP TO PVNT RPTD/PRLNGD SKIN CONT W/THIS SUBSTANCE.
Supplemental Safety and Health
EFTS OF OVEREXP: MAY BE CONTRA-INDICATED EXCEPT FOR LIFE-SUSTAINING
    USES IN HUMANS ACUTELY/CHRONICALLY EXPOSED TO CFC'S . CHRONIC:
    PRLNGD HUMAN EXPOS FOR 2 WKS @ CONCS OF APPROX 500 & 1000 PPM C
    AUSED MILD THROAT IRRIT ON 1ST DAY, BUT NO DECREMENT IN PERFORMANCE
    OF COMPLEX MENTAL TASKS. (OTHER INFO)

==================  Physical/Chemical Properties  ==================

Boiling Pt:=45.8C, 114.4F
Melt/Freeze Pt:=13.2C, 55.8F
Vapor Pres:284 MMHG @ 20C
Vapor Density:6(APPROX)
Spec Gravity:1.6 @ 77F
Evaporation Rate &amp; Reference:0.45 (ACETONE =1)
Solubility in Water:0.028%
Appearance and Odor:COLORLESS LIQUID WITH AN ODOR LIKE AMMONIA AT HIGH
    CONCENTRATIONS.

=================  Stability and Reactivity Data  =================

Stability Indicator/Materials to Avoid:YES
ALKALI METALS: VIOLENT RXN POSS. ALUMINUM (POWDERED): FORMS
    SHOCK-SENSITIVE MIX. BARIUM (POWDERED): FORMS EXPLO MIX. BERYLLIUM
    & CALCIUM: VIOLENT RXN POSS. LITHIUM (POWDERED): FORMS (STATE
    REGULATORY INFO)
Stability Condition to Avoid:STABLE UNDER NORMAL TEMPS & PRESSURES. MAY
    BURN BUT DOES NOT IGNITE READILY. AVOID CONTACT WITH STRONG
    OXIDIZERS, EXCESSIVE HEAT, SPARKS, OR OPEN FLAME.
Hazardous Decomposition Products:THERMAL DECOMPOSITION PRODUCTS MAY
    INCLUDE TOXIC AND CORROSIVE FUMES OF CHLORIDES AND FLUORIDES, AND
    TOXIC OXIDES OF CARBON. PHOSGENE .
Conditions to Avoid Polymerization:HAZARDOUS POLYMERIZATION HAS NOT
    BEEN REPORTED TO OCCUR UNDER NORMAL TEMPERATURES AND PRESSURES.

===================  Toxicological Information	===================

Toxicological Information:IRRIT DATA: 500 MG OPEN SKIN-RABBIT MILD; 500
    MG/24 HRS SKIN-RABBIT MILD. TOXICITY DATA: 87000 PPM/6 HRS
    INHAL-RAT LCLO: 25 PPH/90 SECONDS INHAL-MOUSE LCLO; 20 PPH/6 HRS/2
    YRS-INTERMITTENT INHAL-RAT T CLO: 43 GM/KG ORAL-RAT LD50:
    CARCINOGEN STATUS: NONE. ACUTE TOX LEVEL: RELATIVELY NON-TOXIC BY
    INHAL & INGEST. TARGET EFTS: CNS DEPRESSANT; SIMPLE ASPHY.
    POISONING MAY ALSO AFFECT LIVER & KIDNEYS. ADD ITIONAL DATA:
    STIMULANTS SUCH AS EPINEPHRINE MAY INDUCE VENTRICULAR FIBRILLATION.

=====================  Ecological Information  =====================

Ecological:N/P -OTHER INFO: 5 GM/KG W/RABBIT SKIN FOR 5 SUCCESSIVE DAYS
    RSLTD IN LOC NECROSIS & SLOUGHING PLUS CONSPICUOUS ENLARGEMENT OF
    LIVER CELLS. EYE CONT: ACUTE: MAY CAUSE IRRIT. APPLIC OF 0.1 ML TO
    RABBIT  EYES IS REPORTED TO HAVE PRDCED ONLY MILD CONJ & MINIMAL
    CORNEAL DULLNESS @ 24 HRS. ALL EYES RETURNED TO NORMAL W/IN 48 HRS.
    CHRONIC: NO DATA AVAIL. INGEST:NARCOTIC. ACUTE: ONE HUMAN
    ACCIDENTALLY REC EIVED 1 LITER OF
    1,1,2-TRICHLORO-1,2,2-TRIFLUOROETHANE IN STOM WHILE UNDER ANESTH.
    THIS PRDCED IMMED BUT TRANSIENT CYANOSIS. INDIVIDUAL SURVIVED &
    RPTD ONLY SEV RECTAL IRRIT & DIARR FOR 3 DAYS THEREAF TER.
    (TRANSPORT INFO)

====================  Disposal Considerations  ====================

Waste Disposal Methods:OBSERVE ALL FEDERAL, STATE AND LOCAL REGULATIONS
    WHEN STORING OR DISPOSING OF THIS SUBSTANCE.

===================  MSDS Transport Information  ===================

Transport Information:N/P -ECOLOGICAL INFO: IF SUFFICIENT AMTS ARE
    INGESTED, SYSTEMIC TOX MAY OCCUR AS DETAILED IN ACUTE INHAL. INGEST
    OF HYDROCARBONS IS ASSOC W/PNEUM, CNS DEPRESS & ARRHYS. CHRONIC: NO
    CHANGES WERE PRDCED  IN OFFSPRING OF PREGNANT RABBITS EXPOSED
    ORALLY. FIRST AID PROC: & SUPPORTIVELY. GET MED ATTN IF NEEDED.
    ANTIDOTE: NO SPECIFIC ANTIDOTE. TREAT SYMPTOMATICALLY &
    SUPPORTIVELY. EXTING MEDIA: TYPE OF SU RROUNDING FIRE. AVOID BRTHG
    HAZ VAPS, KEEP UPWIND. RESP PROT: SUPPLIED-AIR RESP. ANY NIOSH
    APPRVD SCBA. ESCAPE-ANY NIOSH APPRVD AIR-PURIFYING FULL FACEPIECE
    RESP (GAS MASK) (FED REGULATORY INFO)

=====================  Regulatory Information  =====================

SARA Title III Information:SUBJECT TO SARA SECTION 313 ANNUAL TOXIC
    CHEMICAL RELEASE REPORTING. COMPONENTS AND CONTAMINANTS. EXPOSURE
    LIMITS: 1000 PPM (7670 MG/M3) OSHA TWA; 1250 PPM (9590 MG/M3) OSHA
    STEL. 1000 PPM (7670 MG/M3 ) ACGIH TWA; 1250 PPM (9590 MG/M3) ACGIH
    STEL. 1000 PPM (7670 MG/M3) NIOSH REC TWA; 1250 PPM (9590 MG/M3)
    NIOSH REC STEL. 500 PPM (3832 MG/M3) DFG MAK TWA; 1000 PPM (7670
    MG/M3) DFG MAK 60 MIN PEAK, M OMENTARY VALUE, 3 TIMES/SHIFT.
    MEASUREMENT METH: CHARCOAL TUBE; CARBON DISULFIDE; GAS
    CHROMATOGRAPHY WITH FLAME IONIZATION DETECTION; (NIOSH. VOL. III #
    1020).
Federal Regulatory Information:OSHA REVOKED THE FINAL RULE LIMIT OF
    JANUARY 19, 1989 IN RESPONSE TO THE 11TH CIRCUIT COURT OF APPEALS
    DECISION (AFL CIO V. OSHA). EFFECTIVE (CONT NEHC FOR COMPLETE
    INFO). --		      TRANSPORT  INFO: WITH NIOSH APPRVD CHIN
    STYLE/FRONT OR BACK-MOUNTED ORG VAP CANISTER. ANY APPROP
    ESCAPE-TYPE NIOSH APPRVD SCBA. FOR FIREFIGHTING & OTHER IMMED
    DANGEROUS TO LIFE/HLTH CNDTNS: ANY NIOSH APPRVD SCB A THAT HAS FULL
    FACEPIECE & IS OPERATED IN PRESS-DEMAND/OTHER POS-PRESS MODE. ANY
    NIOSH APPRVD SUPPL IED-AIR RESP THAT HAS A FULL FACEPIECE & IS
    OPERATED IN PRESS-DEMAND OR OTHER POS-PRESS MODE (STATE REGULATORY
    INFO)
State Regulatory Information:N/P -FED REGULATORY INFO: IN COMBINATION
    WITH AN NIOSH APPRVD AUXILIARY SCBA OPERATED IN PRESS-DEMAND OR
    OTHER POSITIVE-PRESSURE MODE. MATLS TO AVOID: EXPLOSIVE MIX.
    MAGNESIUM: VIOLENT RXN POSS. MAGNE SIUM ALLOY: DECOMP POSS.
    PLASTICS, RUBBER, COATINGS: MAY BE ATTACKED. POTASSIUM: FORMS
    IGNITABLE CMPD. SAMARIUM: EXPLODES ON FRICTION. SODIUM: FORMS
    IGNITABLE COMPOUND. SODIUM-POTASSIUM ALLOY: VIOLENT  EXPLOSION.
    TITANIUM (POWDERED): FORMS SHOCK-SENSITIVE MIXTURE. ZINC: VIOLENT
    REACTION POSSIBLE.

=======================  Other Information  =======================

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